15-epi-Lipoxin A4 ELISA Kit

15-epi-Lipoxin A4 ELISA is used for the quantitative analysis of 15-epi-Lipoxin A4 levels in biological fluid.

15-epi-Lipoxin A₄ is an aspirin-triggered eicosanoid believed to be involved in the positive attributes of aspirin therapy for heart, cancer, and human immunodeficiency virus patients. During inflammation, neutrophils are activated. 15-epi-LXA₄, when administered in vivo, inhibits neutrophil activation and dampens inflammation (Takano, 1997). 15-epi-LXA₄ is naturally formed in the body via this pathway:
Arachidonic Acid (AA)→15(R) -HETE→15-epi-LXA₄

Aspirin is thought to be involved in the acetylation of prostaglandin G/H synthase, which triggers the conversion of AA to 15(R)-HETE. The development of this assay, which is both sensitive and selective for 15-epi-LXA₄, will be essential to researchers studying anti-inflammatory medications.